Tadalafil is the name of the chemical component contained in brand name Cialis as well as in generic Cialis available easily through online pharmacies. It is used to treat erectile dysfunction and benign prostatic hyperplasia (BPH). Tadalafil, like Sildenafil and Vardenafil, is highly potent phosphodiesterase type 5 (PDE5) inhibitor. Tadalafil was the third pill to be approved by the FDA after Sildenafil and Vardenafil. Erectile dysfunction is the inability to get or keep an erection firm enough in order to have sexual intercourse. Erectile dysfunction is a very common problem in men. Majority of men suffer from erectile dysfunction at least once in their lifetime. BPH is the condition where the prostate becomes larger than usual which squeezes the urethra. This prevents the regular flow of urine from the bladder. It mostly affects middle aged and elderly people. BPH does not lead to cancer or increase the risk of cancer. Tadalafil was approved by the FDA in 2003 for the treatment of erectile dysfunction as the third erectile dysfunction prescription medicine after Sildenafil and Vardenafil.
Tadalafil is available in 2.5 mg, 5 mg, 10 mg and 20 mg dosage in brand Cialis. However, generic Cialis are also available in 40 mg and 60 mg dosages. Tadalafil is also sold under the brand name Tadacip in 10 mg and 20 mg dosages by Cipla. Another brand of Tadalafil is Adcirca which is marketed as a treatment for pulmonary arterial hypertension and improve stamina and exercise capacity. Cialis is prescribed for the treatment of both erectile dysfunction and benign prostatic hyperplasia (BPH). The dosage is decided by the doctor according to the severity of the condition and the patient’s reaction. The daily dosage Cialis is prescribed in 5 mg. Cialis is a “use when needed” medicine when used for the treatment of erectile dysfunction whereas for the treatment of BPH it is a daily course medicine. Usually Cialis 10 mg is given to the new ED customers and the dosage is increased gradually. The approved dose for pulmonary arterial hypertension is 40 mg once daily.
Tadalafil, Sildenafil and Vardenafil are all PDE5 inhibitors, but Cialis is distinct from the other two because of its effectiveness for 36 hours as compared to 6 to 8 hours of Sildenafil and Vardenafil which makes it effective for longer duration. Hence, it is also known as “The weekend pill”. Another distinction of Cialis is that it does not inhibit other types of PDE enzymes like PDE1 and PDE6. Sildenafil and Vardenafil inhibit PDE6, an enzyme found in the eye. This inhibition of PDE6 is responsible for the bluish tinge experienced by some users of Sildenafil and Vardenafil. PDE1 is found in the brain, heart and vascular smooth muscle. The inhibition of PDE1 is responsible for the side effects like vasodilation, flushing and tachycardia.
Not everyone experiences a side effect. If you suffer from any side effect, you can always switch to lower dosage strength.
The most common side effects of Tadalafil are:
• Stomach pain
• Acid reflux
• Back pain
• Runny nose
One should not take Tadalafil if:
• If you are taking nitric medication
• If you are allergic to Tadalafil
• If you are advised by your doctor to not engage in sexual activities due to cardiovascular diseases
• If you suffer from hepatic impairment
• If you suffer from impaired kidney functions
• If you suffer from low blood pressure
• If you had a recent stroke or heart attack
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