General Information about Dapoxetine

One of the most embarrassing situations faced by men all around the world is when they have no control over their ejaculation. It is one of the worst fears among men to ejaculate quickly leaving their sexual partners unsatisfied. Generally, the average time required by men to ejaculate is about four to five minutes. But men have usually reported that they wish they could perform for a longer period of time. This inability of a man where he cannot control his ejaculation or when he ejaculates within a minute leaving his sexual partner unsatisfied is known as premature ejaculation.

Some men suffer from premature ejaculation temporarily and their condition gets better on its own while some suffer from it permanently in which case they are prescribed medicines known as Selective Serotonin Reuptake Inhibitors (SSRIs). Dapoxetine is the most popular medicine used for the treatment of premature ejaculation. Dapoxetine is a medicine specifically developed for the treatment of premature ejaculation. Dapoxetine is sold under the brand name Priligy or Westoxetin. Dapoxetine is popular among the men suffering premature ejaculation because unlike the other medicines of its class, it is absorbed quickly and removed rapidly from the body. Selective Serotonin Reuptake Inhibitors are also used as anti depressants, but Dapoxetine is favored more for its use to treat premature ejaculation rather than use as an anti depressant due to the fact that it gets absorbed quickly and eliminated rapidly which makes it suitable for fast acting properties. It is not a course medication, and needs to be taken only when sexual intercourse is expected. Generally, it is advised to take Dapoxetine one to three hours before the sexual intercourse.

Various studies have concluded the efficiency of Dapoxetine for the treatment of premature ejaculation. Dapoxetine is sold in two different strengths of 30 mg and 60 mg. The higher dosage is found to increase the intravaginal ejaculation latency time (IELT) in men with lifelong premature ejaculation whereas the efficiency and the results were found to be almost the same in men suffering from acquired premature ejaculation. As such, most men prefer to use the higher dosage of 60 mg for their treatment of premature ejaculation. Some manufacturers provide Dapoxetine in 90 mg dosages, but these are not so popular. Many patients have opted to use other Selective Serotonin Reuptake Inhibitors like Fluoxetine, Paroxetine, Sertraline, Fluvoxamine and Citalopram as off label drugs to treat premature ejaculation since these provide a better result efficiency. These medications provide two to nine folds of increase in intravaginal ejaculation latency time as compared to dapoxetine’s result of three to eight fold increase. However, it is not advisable to use these SSRIs for the treatment of premature ejaculation because unlike Dapoxetine these medications have a higher half life which means these are not eliminated as quickly as Dapoxetine. Also, these medications need to be taken daily to be proven effective for the treatment of premature ejaculation. Both these factors combined result in a risk of the drug accumulation. Over accumulation of these drugs might result in increase in the adverse effects of these medications like a decrease in sexual desire or sexual libido and erectile dysfunction. Dapoxetine on the other is a fast acting SSRI with low half life making it a favorable drug for the treatment of premature ejaculation reducing the rate of side effects and the risk of accumulation in the body.

Sometimes it is advised to not take Dapoxetine as it might not be suitable with their conditions or their current medications. The conditions under which it is not advised are:
• If you suffer from inclination to fainting
• If you suffer from cardiovascular diseases
• If you suffer from bleeding or clotting disorders
• If you suffer from epilepsy
• If you suffer from diseases such as bipolar disorder, depression or mania
• If you suffer from glaucoma which is increased pressure in the eye
• If you suffer from hepatic impairment
• If you are allergic to Dapoxetine

Dapoxetine should not be taken with the following medicines:
• Ketoconazole
• Ritonavir
• Telithromycin
• Thioridazine
• Monoamine
• Oxidase inhibitors
• Serotonin norepinephrine reuptake inhibitors
• Tricyclic antidepressants

The side effects of Dapoxetine are as follows:
• Nausea
• Dizziness
• Dry mouth
• Headache
• Diarrhea
• Insomnia

Dapoxetine is also sold in combination with sidenafil and tadalafil. Such pills have dual benefits of treating erectile dysfunction and premature ejaculation.

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