Cialis

Cialis can treat pulmonary arterial hypertension

Tadalafil sold under the brand name Cialis is advertised as a treatment for erectile dysfunction however, it has other promising benefits too. Cialis in addition to Viagra and Levitra are known as the PDE5 inhibitor drugs. These drugs work by dilating the smooth muscle lining blood vessels which improves the blood flow. Since these drugs have a direct effect on improving the circulation system in general, it is imperative that these drugs may hold a cure for other related diseases apart from erection problems.

Scientists have been successful in finding such potential benefits of these drugs where they can prove to be effective in treating the disorders unrelated to erectile dysfunction. In fact, PDE5 inhibiting drugs itself were discovered in the research for diseases unrelated to sexual functions. Viagra was the first drug of its class to be discovered. It was originally developed by a group of chemists working for Pfizer based in England for the treatment of high blood pressure and angina pectoris. But researchers found that the drug had a peculiar side effect of consistently giving erections. This is how the drug eventually came to be prescribed for the treatment of erectile dysfunction.

Patients suffering from pulmonary arterial hypertension (PAH) have high blood pressure in the arteries between the heart and the lungs. However, it is different from regular high blood pressure. In this condition, the tiny arteries in the lungs become narrow or blocked. Pulmonary arterial hypertension is rare but it is a life threatening condition.

Pulmonary arterial hypertension has many unknown causes, it could be genetic, or it may develop in a person as a result of other medical conditions. The conditions which can lead to this disease are:

  1. Congestive heart failure
  2. Blood clots in the lungs
  3. HIV
  4. Drugs like cocaine or methamphetamine
  5. Liver disease
  6. Lung diseases like chronic bronchitis, emphysema or pulmonary fibrosis
  7. Sleep apnea

 

Patients diagnosed with PAH are prescribed Ambrisentan, which is sold under the brand name Letairis. The muscles in blood vessels are constricted by a peptide endothelin. Ambrisentan, an endothelin receptor antagonist, relaxes those muscles. It blocks the action of endothelin keeping the blood vessels from constricting. People suffering from PAH report an improved exercise capacity after taking ambrisentan.

The manufacturers of Ambrisentan and Cialis jointly sponsored a research. The aim was to study if the combination of both the drugs was better in the treatment of PAH rather than treating it with ambrisentan or cialis alone. The study involved 500 patients suffering from PAH, half of which were given the combination of both, 250 patients were given ambrisentan alone and 250 patients received cialis alone. Only about 18 percent of the patients of the group which received both the drugs suffered from severe pulmonary arterial hypertension or died, compared to 31 percent of the patients given either ambrisentan or cialis alone. Also it was noted that the group given the combination of drugs did not suffer from any additional side effects. Among the patients administered both the drugs, those who had not received prior treatments resulted in a significantly lower risk of clinical failure events than the risk with ambrisentan or cialis alone.

Another drug, sildenafil (the active ingredient in Viagra), is also prescribed for the treatment of PAH. It is sold under the brand name Revatio as a treatment for PAH. Both viagra and cialis belong to the same class of drugs known as PDE5 inhibitors. So, it was obvious that cialis too could be used for the treatment of PAH. However, both the drugs have few differences. Cialis has a longer half life period as compared to viagra which means it remains effective for as long as 36 hours compared to viagra which can last for about 8 hours. It is still not clear whether viagra or cialis is better in treating PAH. For some people with PAH, cialis may work better while the opposite may be true for the others. The same is true regarding both the drugs in the treatment of erectile dysfunction in men.

The drugs intended to be used for erectile dysfunction can have other potential uses too. It only remains a matter of time before their far reaching effects are fully understood and put to use. Apart from treating PAH, viagra is also used to treat a number of other diseases like altitude sickness, menstrual cramps, etc.

Visit our website to buy Cialis online. Click on the links below:

Viagrameds_logo

Generic Cialis
Generic Viagra
Brand Alternative Cialis
Brand Alternative Viagra

Leave a Reply